Megha Suresh headshot

Biochemistry and Molecular Biology/Biotechnology

Research Topic: Chloropicrin and Cell Death: An In Vitro Study

Research Poster Located in the Neighborhood Engagement Centers

Research Summary:

Megha's research aimed to understand how chloropicrin, a toxic chemical used as both a warfare agent and pesticide, causes cell death. The study involved MTT assays to determine the concentration of chloropicrin needed to kill 50% of cells and RT-qPCR to analyze gene expression related to ferroptosis, a type of cell death dependent on increased intracellular iron levels. The findings confirmed that chloropicrin induces cell death through ferroptosis, as there was a notable increase in the expression of genes associated with this process.